Get health care support instantly for those who notice any of the following: sluggish/shallow respiratory, significant drowsiness/problems waking up, confusion.
Applying this medicine with any of the subsequent medicines will not be advisable. Your doctor may well come to a decision not to treat you with this medication or improve many of the other medicines you take.
Get professional medical assist right away if you detect any of the following: slow/shallow respiration, significant drowsiness/issue waking up, confusion.
It is very important that the health care provider Examine your progress at common visits to ensure this medicine is working properly. Blood exams can be necessary to look for unwelcome outcomes .
This drug may possibly trigger drowsiness, dizziness, or impair pondering or motor capabilities; clients need to stay away from driving or operating equipment even though taking this drug.
Narcotic analgesics or cough suppressants, including codeine, really should not be Employed in asthmatic clients (see CONTRAINDICATIONS). Nor really should they be Utilized in acute febrile disease connected with productive cough or in chronic respiratory sickness where by interference with capacity to very clear the tracheobronchial tree of secretions would have a deleterious impact on the client's respiratory perform.
One example is, lots of reported instances of Loss of life occurred within the submit-operative time period pursuing tonsillectomy and/or adenoidectomy, and several of the children experienced proof of staying ultra-speedy metabolizers of codeine. On top of that, young children with obstructive snooze apnea who will be addressed with codeine for publish-tonsillectomy and/or adenoidectomy soreness can be notably delicate to its respiratory depressant effect. As a result of possibility of lifestyle-threatening respiratory despair and Loss of life:
Promethazine can be an H1 receptor blocking agent. In addition to its antihistaminic motion, it offers clinically beneficial sedative and antiemetic outcomes.
The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people a lot less than six decades of age, due to the fact the combination may possibly lead to lethal respiratory despair in this age inhabitants.
Making use of Liquor or tobacco with specified medicines can also trigger interactions to occur. Focus on with your Health care Expert using your medicine with food, Liquor, or tobacco.
Problems OF USE: The knowledge On this database is meant to supplement, not substitute for, the experience and judgment of Health care industry experts. The knowledge just isn't meant to deal with all attainable employs, directions, safeguards, drug interactions or adverse outcomes, nor need to or not it's construed to indicate that use of a certain drug is Protected, ideal or effective to suit your needs or anybody else.
Drug interactions may improve how your drugs do the job or enhance your possibility for severe Uncomfortable side effects. This doc does not have all doable drug interactions.
Extensive-phrase animal scientific studies haven't been done to evaluate the carcinogenic likely of codeine or of promethazine, nor are there other animal or human info about carcinogenicity, mutagenicity, or impairment of fertility with these agents.
Postmarketing instances of respiratory depression, including fatalities are actually click here described with utilization of promethazine in pediatric patients.